Engineering Gold Nanostructures for Cancer Treatment: Spherical Nanoparticles, Nanorods, and Atomically Precise Nanoclusters

Nanomaterials (Basel). 2022 May 19;12(10):1738. doi: 10.3390/nano12101738.

Abstract

Cancer is a major global health issue and is a leading cause of mortality. It has been documented that various conventional treatments can be enhanced by incorporation with nanomaterials. Thanks to their rich optical properties, excellent biocompatibility, and tunable chemical reactivities, gold nanostructures have been gaining more and more research attention for cancer treatment in recent decades. In this review, we first summarize the recent progress in employing three typical gold nanostructures, namely spherical Au nanoparticles, Au nanorods, and atomically precise Au nanoclusters, for cancer diagnostics and therapeutics. Following that, the challenges and the future perspectives of this field are discussed. Finally, a brief conclusion is summarized at the end.

Keywords: atomically precise gold nanoclusters; cancer treatment; challenges and perspective; gold nanostructures; spherical nanoparticles and nanorods.

Publication types

  • Review

Grants and funding

This work was supported by the Chongqing Chemical Industry Vocational College.