Metabolomics in Bariatric and Metabolic Surgery Research and the Potential of Deep Learning in Bridging the Gap

Metabolites. 2022 May 19;12(5):458. doi: 10.3390/metabo12050458.

Abstract

During the past several years, there has been a shift in terminology from bariatric surgery alone to bariatric and metabolic surgery (BMS). More than a change in name, this signifies a paradigm shift that incorporates the metabolic effects of operations performed for weight loss and the amelioration of related medical problems. Metabolomics is a relatively novel concept in the field of bariatrics, with some consistent changes in metabolite concentrations before and after weight loss. However, the abundance of metabolites is not easy to handle. This is where artificial intelligence, and more specifically deep learning, would aid in revealing hidden relationships and would help the clinician in the decision-making process of patient selection in an individualized way.

Keywords: bariatric surgery; diabetes mellitus; metabolic surgery; metabolomics; nonalcoholic steatohepatitis; obesity.

Grants and funding

This research was funded by HOSPITAL LINE S.A., 36 Kosti Palama Street, PC 14343, Nea Chalkidona, Athens, Greece. VAT # 094396063, Tax Office of Athens.