An Intelligent ECG-Based Tool for Diagnosing COVID-19 via Ensemble Deep Learning Techniques

Biosensors (Basel). 2022 May 5;12(5):299. doi: 10.3390/bios12050299.

Abstract

Diagnosing COVID-19 accurately and rapidly is vital to control its quick spread, lessen lockdown restrictions, and decrease the workload on healthcare structures. The present tools to detect COVID-19 experience numerous shortcomings. Therefore, novel diagnostic tools are to be examined to enhance diagnostic accuracy and avoid the limitations of these tools. Earlier studies indicated multiple structures of cardiovascular alterations in COVID-19 cases which motivated the realization of using ECG data as a tool for diagnosing the novel coronavirus. This study introduced a novel automated diagnostic tool based on ECG data to diagnose COVID-19. The introduced tool utilizes ten deep learning (DL) models of various architectures. It obtains significant features from the last fully connected layer of each DL model and then combines them. Afterward, the tool presents a hybrid feature selection based on the chi-square test and sequential search to select significant features. Finally, it employs several machine learning classifiers to perform two classification levels. A binary level to differentiate between normal and COVID-19 cases, and a multiclass to discriminate COVID-19 cases from normal and other cardiac complications. The proposed tool reached an accuracy of 98.2% and 91.6% for binary and multiclass levels, respectively. This performance indicates that the ECG could be used as an alternative means of diagnosis of COVID-19.

Keywords: COVID-19; Convolutional Neural Networks (CNN); ECG trace image; deep learning; feature selection; transfer learning.

MeSH terms

  • Algorithms
  • COVID-19* / diagnosis
  • Communicable Disease Control
  • Deep Learning*
  • Electrocardiography
  • Humans

Grants and funding

This research received no external funding.