An unusual case of hyperthyroidism with recurrent vomiting and hypercalcemia as the main manifestations

J Int Med Res. 2022 May;50(5):3000605221099120. doi: 10.1177/03000605221099120.

Abstract

Complicated vomiting and hypercalcemia are clinically rare in patients with hyperthyroidism. We describe a case of a woman whose main symptoms were palpitations, sweating, and vomiting. She was diagnosed with Graves' disease by an analysis of thyroid function, thyroid-related antibodies, and color Doppler ultrasound. Biochemical tests showed that her serum calcium levels were greatly elevated. Her symptoms were relieved following the administration of antithyroid drugs, propranolol for heart rate control, fluid replacement, diuresis and calcium reduction, antiemesis, and liver protection. This case suggests that the thyroid function should be screened when hypercalcemia is seen in the clinic.

Keywords: Graves’ disease; Hyperthyroidism; hypercalcemia; liver damage; palpitation; vomiting.

Publication types

  • Case Reports

MeSH terms

  • Antithyroid Agents
  • Calcium
  • Female
  • Graves Disease* / complications
  • Graves Disease* / diagnosis
  • Humans
  • Hypercalcemia* / complications
  • Hypercalcemia* / diagnosis
  • Hyperthyroidism* / complications
  • Hyperthyroidism* / diagnosis
  • Hyperthyroidism* / drug therapy
  • Vomiting / etiology

Substances

  • Antithyroid Agents
  • Calcium