Factor analysis of the CORE measure of psychomotor disturbance in psychotic depression: Findings from the STOP-PD II study

Kathleen S Bingham; Nicholas H Neufeld; George S Alexopoulos; Patricia Marino; Benoit H Mulsant; Anthony J Rothschild; Aristotle N Voineskos; Ellen M Whyte; Barnett S Meyers; Alastair J Flint

doi:10.1016/j.psychres.2022.114648

Factor analysis of the CORE measure of psychomotor disturbance in psychotic depression: Findings from the STOP-PD II study

Psychiatry Res. 2022 Aug:314:114648. doi: 10.1016/j.psychres.2022.114648. Epub 2022 May 21.

Affiliations

¹ Centre for Mental Health, University Health Network, Toronto, Canada; Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Canada.
² Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Canada.
³ Department of Psychiatry, Westchester Division, Weill Cornell Medicine of Cornell University and New York Presbyterian Hospital, New York, USA.
⁴ University of Massachusetts Chan Medical School and UMass Memorial Health Care, Worcester, USA.
⁵ Department of Psychiatry, University of Pittsburgh School of Medicine and UPMC Western Psychiatric Hospital, Pittsburgh, USA.
⁶ Centre for Mental Health, University Health Network, Toronto, Canada; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Canada. Electronic address: alastair.flint@uhn.ca.

PMID: 35623239
DOI: 10.1016/j.psychres.2022.114648

Abstract

The CORE instrument is commonly used to measure psychomotor disturbance. We examined the factor structure of the CORE in 266 adults with an acute episode psychotic depression, a disorder with a high rate of psychomotor disturbance. Exploratory factor analysis identified a two-factor solution: Factor 1 corresponded to the CORE's retardation and non-interactiveness items and Factor 2 corresponded to its agitation items. Internal consistency was excellent for Factor 1 but questionable for Factor 2. These findings suggest that the CORE's retardation and non-interactiveness items should be combined in one subscale when assessing patients with an acute episode of psychotic depression.

Keywords: CORE instrument; Psychomotor disturbance; Psychotic depression.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adult
Bipolar Disorder*
Depression
Depressive Disorder, Major* / complications
Factor Analysis, Statistical
Humans
Psychotic Disorders* / complications