Technique, outcome and changes in prostate dimensions in patients with urinary retention managed by aquablation

Int Urol Nephrol. 2022 Aug;54(8):1787-1792. doi: 10.1007/s11255-022-03244-y. Epub 2022 May 27.

Abstract

Purpose: This study aimed to investigate the functional and urodynamic outcome of Aquablation in patients with acute urinary retention (AUR) on catheters.

Methods: Men aged 50-70 who failed medical treatment of BPO with AUR failing to wean off urethral catheter were recruited to undergo Aquablation. Individuals were assessed pre-operatively and at 3 and 6 months after surgery. The primary outcome was defined by the success rate of weaning off catheter. Secondary outcomes were measured by a change in prostate size, symptom scores and urodynamic parameters.

Results: Twenty patients underwent Aquablation between June 2019 and September 2020. Mean duration of the urethral catheter in-situ was 5.9 ± 4.9 weeks and mean prostate size of the cohort pre-operatively was 60.8 ± 15.8 cc. A second pass Aqaublation treatment was performed in 14 patients. Five patients failed to wean off the catheter on the first attempt after surgery, requiring another attempt 1 week later which were all successful. At 3 months after the operation, a significant reduction in prostate volume was observed (60.8 ± 15.8 cc vs 24.9 ± 10.3 cc, p < 0.001). No change in international index of erectile function (IIEF) was found (baseline: 16.1 ± 5.8; 3-month: 14.9 ± 6.4; p = 0.953). Mean bladder outlet obstruction index was 14.2 ± 23.0 at 6 months upon urodynamic assessment with 75% of patients had a resolution of detrusor overactivity. Reduction in prostate length was found to be more significant than a reduction in width and height after Aquablation (R = 0.693, p = 0.039).

Conclusion: From the early data of a single centre, Aquablation was shown to provide a consistent improvement in symptoms, uroflowmetry and urodynamic parameters in patient with a urethral catheter. Results from our study suggest that improvement from Aquablation is reproducible in patients with AUR.

Keywords: Acute urinary retention; Benign prostatic obstruction; Robotics; Waterjet ablation.

MeSH terms

  • Ablation Techniques* / methods
  • Humans
  • Male
  • Prostate / surgery
  • Prostatic Hyperplasia* / complications
  • Prostatic Hyperplasia* / surgery
  • Treatment Outcome
  • Urinary Bladder Neck Obstruction* / complications
  • Urinary Retention* / complications
  • Urinary Retention* / surgery