A rare case of Epstein-Barr virus-positive anaplastic plasmacytoma in the sinonasal tract

Ear Nose Throat J. 2022 May 25:1455613221104683. doi: 10.1177/01455613221104683. Online ahead of print.

Abstract

Epstein-Barr virus-positive anaplastic plasmacytoma in the sinonasal tract is uncommon. Herein, we present the case of a 40-year-old male patient with a right sinonasal tract filled with a soft tissue mass, as shown on CT. Apart from frequent nosebleeds, he did not report any specific sinonasal symptoms, such as nasal obstruction, discharge, or loss of smell. The patient underwent functional endoscopic sinus surgery under general anesthesia. The diagnosis of Epstein-Barr virus-positive anaplastic plasmacytoma was confirmed by lesion biopsy, subsequent immunohistochemical staining, and in situ hybridization.

Keywords: Epstein-Barr virus-positive; anaplastic plasmacytoma; magnetic resonance imaging; nasal cavity; sinonasal tract.