Increased TSPO PET signal after radiochemotherapy in IDH-wildtype glioma-indicator for treatment-induced immune activation?

Stefanie Quach; Adrien Holzgreve; Louisa von Baumgarten; Maximilian Niyazi; Marcus Unterrainer; Niklas Thon; Sophia Stöcklein; Peter Bartenstein; Jörg-Christian Tonn; Nathalie L Albert

doi:10.1007/s00259-022-05844-3

Increased TSPO PET signal after radiochemotherapy in IDH-wildtype glioma-indicator for treatment-induced immune activation?

Eur J Nucl Med Mol Imaging. 2022 Oct;49(12):4282-4283. doi: 10.1007/s00259-022-05844-3. Epub 2022 May 25.

Authors

Stefanie Quach^{1

2}, Adrien Holzgreve³, Louisa von Baumgarten^{4

5

6}, Maximilian Niyazi^{5

6

7}, Marcus Unterrainer⁸, Niklas Thon^{4

5

6}, Sophia Stöcklein⁸, Peter Bartenstein^{3

5

6}, Jörg-Christian Tonn^{4

5

6}, Nathalie L Albert^{3

5

6}

Affiliations

¹ Department of Neurosurgery, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany. Stefanie.Quach@med.uni-muenchen.de.
² Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany. Stefanie.Quach@med.uni-muenchen.de.
³ Department of Nuclear Medicine, University Hospital, LMU Munich, Munich, Germany.
⁴ Department of Neurosurgery, University Hospital, LMU Munich, Marchioninistr. 15, 81377, Munich, Germany.
⁵ German Cancer Consortium (DKTK) partner site Munich, Munich, Germany.
⁶ German Cancer Research Center (DKFZ), Heidelberg, Germany.
⁷ Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
⁸ Department of Radiology, University Hospital, LMU Munich, Munich, Germany.

No abstract available

MeSH terms

Brain Neoplasms* / diagnostic imaging
Brain Neoplasms* / therapy
Chemoradiotherapy
Glioma* / diagnostic imaging
Glioma* / therapy
Humans
Isocitrate Dehydrogenase / genetics
Mutation
Positron-Emission Tomography
Receptors, GABA

Substances

Receptors, GABA
TSPO protein, human
Isocitrate Dehydrogenase