Review of present method of glucose from human blood and body fluids assessment

Biosens Bioelectron. 2022 Sep 1:211:114348. doi: 10.1016/j.bios.2022.114348. Epub 2022 May 13.

Abstract

the work has been aimed to create an overview of available and used methods and ways to determine the concentration of glucose in body fluids, especially from a technical point of view. It also provides an overview of the clinical features of these methods. The survey found that today's market offers a large number of options and approaches to the issue. There are accurate reference laboratory methods, self-monitoring methods for measuring glucose levels using glucometers, or continuous methods for daily monitoring of blood glucose trends and for insulin pump control. However, it must not be forgotten that the development of full closure of feedback is still not complete today. Individual methods cannot always be compared with each other, precisely because of the focus and the use of these methods. Choosing the right method of blood glucose levels in the body measuring can help patients to manage their diabetes mellitus. The methods listed in the overview are divided in terms of measurement continuity and further according to the invasiveness of the method. Finally, the issues of accuracy in the detection of glycaemia variability and the possibility of further development of these methods are discussed, as it is clear from the survey that the development is focused mainly on continuous methods improving that get to the forefront and also on developing a biosensor that is purely non-invasive and continuous.

Keywords: Continuous glucose monitoring (CGM); Glucose monitoring; Glucose selfmonitoring (SMBG); Glycemic control; Non-invasive measurement glucose.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Blood Glucose
  • Blood Glucose Self-Monitoring / methods
  • Body Fluids*
  • Diabetes Mellitus, Type 1*
  • Glucose
  • Humans
  • Hypoglycemic Agents
  • Insulin

Substances

  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin
  • Glucose