Peripheral Inflammatory Biomarkers of Alzheimer's Disease

J Alzheimers Dis. 2022;88(2):389-398. doi: 10.3233/JAD-215422.

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease of unknown pathological origin. The clinical diagnosis of AD is time-consuming and needs to a combination of clinical evaluation, psychological testing, and imaging assessments. Biomarkers may be good indicators for the clinical diagnosis of AD; hence, it is important to identify suitable biomarkers for the diagnosis and treatment of AD. Peripheral inflammatory biomarkers have been the focus of research in recent years. This review summarizes the role of inflammatory biomarkers in the disease course of AD.

Keywords: Alzheimer’s disease; biomarkers; inflammatory; neurodegeneration.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease* / diagnostic imaging
  • Alzheimer Disease* / pathology
  • Biomarkers
  • Disease Progression
  • Humans
  • Neurodegenerative Diseases*

Substances

  • Biomarkers