Surgery for metastatic epidural spinal cord compression in thoracic spine, anterior or posterior approach?

Abstract

Background: The most commonly encountered tumour of the spine is metastasis, and thoracic spine is the most commonly metastatic spine. Controversy exists regarding the optimal surgical approach for this kind of patient. The author conducted a study to assess the differences between anterior thoracotomy and a posterior approach in patients with malignant epidural cord compression in the thoracic spine.

Methods: Between January 2004 and December 2017, 97 patients with metastatic thoracic lesion were stratified into two groups by approach method to the lesion site: Group A - mean anterior thoracotomy, decompression and fixation; and Group P - represented posterior decompression and fixation. Survival time, neurologic status, each complication by surgery or in hospital, and days in intensive care unit(ICU) were compared.

Results: Twenty-five patients were grouped in Group A, and 72 patients belonged to Group P. Lung cancer was the most common primary cancer in both groups. Operation time (213.0 vs. 199.2 min, p = 0.380) and blood loss (912.5 vs. 834.4 ml, p = 0.571) were not statistically significantly different between the two groups. Six patients in Group A (24%) and 6 in Group P (8.3%) developed complications (p = 0.040). Patients in Group A required more days of care in ICUs (2.36 vs. 0.19 days, p < 0.001). The longer survival was seen in Group P (15.4 vs. 11.2 months) but with no significant difference.

Conclusion: A lower surgical complication rate and fewer days of care in ICU were seen in Group P. The authors would prefer a posterior approach for those with thoracic metastatic tumour.

Keywords: Anterior thoracotomy; Length of survival; Metastatic epidural spinal cord compression; Neurologic status; Posterior approach; Thoracic spine.