Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature

Yu-Wen Sung; Yun-Shan Lin; Yen-Ting Chen; Lian-Shung Yeh

doi:10.1016/j.tjog.2022.03.026

Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature

Taiwan J Obstet Gynecol. 2022 May;61(3):539-543. doi: 10.1016/j.tjog.2022.03.026.

Authors

Yu-Wen Sung¹, Yun-Shan Lin², Yen-Ting Chen¹, Lian-Shung Yeh³

Affiliations

¹ Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan.
² Department of Pathology, China Medical University Hospital, Taichung, Taiwan.
³ Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan; School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan. Electronic address: lsyeh@mail.cmuh.org.tw.

PMID: 35595455
DOI: 10.1016/j.tjog.2022.03.026

Abstract

Objective: To report a case and review published cases of non-Hodgkin's lymphoma of the ovary.

Case report: A 30-year-old female presented with abdominal fullness. Abdominal CT revealed bilateral huge ovarian masses with moderate amount of ascites. Explore laparotomy was performed and the frozen section of right ovarian mass reported to be malignant lymphoma. The final diagnosis was Ann Arbor stage IV diffuse large B cell lymphoma. The patient received six cycles of chemotherapy with RCHOP regimen. She achieved complete remission after the treatment, and there's no evidence of recurrence after 12 months follow up.

Conclusion: Ovarian lymphoma is a rare condition. It could present with findings mimicking ovarian cancer. Chemotherapy is the main treatment option and cytoreductive surgery should be avoided.

Keywords: Lymphoma; Non-Hodgkin's; Ovary.

Publication types

Case Reports
Review

MeSH terms

Adult
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Female
Humans
Lymphoma, Large B-Cell, Diffuse* / diagnosis
Lymphoma, Large B-Cell, Diffuse* / drug therapy
Ovarian Neoplasms* / drug therapy
Ovarian Neoplasms* / therapy