Emergence of nutriments as a nascent complementary therapy against antimicrobial resistance

Environ Sci Pollut Res Int. 2022 Jul;29(33):49568-49582. doi: 10.1007/s11356-022-20775-0. Epub 2022 May 20.

Abstract

With these growing and evolving years, antimicrobial resistance has become a great subject of interest. The idea of using natural productive ways can be an effective measure against antimicrobial resistance. The growing prevalence of antimicrobial resistance indicates that advanced natural approaches are a topic of concern for fighting the resistance. Many natural products including essential oils, flavonoids, alkaloids and botanicals have been demonstrated as effective bactericidal agents. In this review, we will discuss in detail about the relevance of such natural products to tackle the problem of antimicrobial resistance, antibiotic adjuvants that aim towards non-essential bacterial targets to reduce the prevalence of resistant bacterial infections, latest bioinformatics approach towards antibacterial drug discovery along with an understanding of biogenic nanoparticles in antimicrobial activity.

Keywords: Alkaloids; Antimicrobial resistance; Flavonoids; Nanoparticles.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Infections* / drug therapy
  • Biological Products* / pharmacology
  • Complementary Therapies*
  • Drug Resistance, Bacterial
  • Humans

Substances

  • Anti-Bacterial Agents
  • Biological Products