Atrial fibrillation in hypertrophic cardiomyopathy - A contemporary mini-review

Hellenic J Cardiol. 2022 Sep-Oct:67:66-72. doi: 10.1016/j.hjc.2022.05.002. Epub 2022 May 15.

Abstract

Hypertrophic cardiomyopathy (HCM) represents the most common genetically inherited cardiovascular disorder and a leading cause of heart failure and sudden cardiac death. Atrial fibrillation (AF) is the most common arrhythmia encountered in HCM patients, primarily due to the process of left atrium dilatation and remodeling. Its presence typically leads to progressive functional decline, increased frequency of heart failure hospitalizations, and increased thromboembolic risk. In this mini-review, we summarize the contemporary data on AF pathophysiology, risk factors, and management in HCM patients suffering from AF.

Keywords: Arterial thromboembolism; Atrial fibrillation; Hypertrophic cardiomyopathy.

Publication types

  • Review

MeSH terms

  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / epidemiology
  • Cardiomyopathy, Hypertrophic* / complications
  • Cardiomyopathy, Hypertrophic* / epidemiology
  • Death, Sudden, Cardiac / epidemiology
  • Death, Sudden, Cardiac / etiology
  • Death, Sudden, Cardiac / prevention & control
  • Heart Failure* / complications
  • Humans
  • Risk Factors
  • Thromboembolism* / complications
  • Thromboembolism* / etiology