Schistosome dipeptide of love

Trends Parasitol. 2022 Jul;38(7):493-495. doi: 10.1016/j.pt.2022.05.001. Epub 2022 May 14.

Abstract

The female schistosome's dependence on the male to reach sexual maturity has puzzled scientists for decades. Using various molecular techniques, Chen et al. dissect the synthesis pathway of the β-alanyl-tryptamine dipeptide (BATT), emitted by the male into its environment, which induces sexual maturation and egg-laying in the female.

Keywords: flatworm; nonribosomal peptide; parasites; schistosome; secondary metabolism.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Dipeptides*
  • Female
  • Male
  • Schistosoma

Substances

  • Dipeptides