Transition metal copper composite ionic liquid self-built ratiometric sensor for the detection of paracetamol

Abstract

In this paper, a MOF derivative Cu-PF₆-MOF composed of transition metal copper and ionic liquid [BMIM] PF₆ was used to construct a ratiometric electrochemical sensor for paracetamol detection. Cu-PF₆-MOF was synthesized by chemical bath method and characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET), X-ray Photoelectron Spectroscopy (XPS) and X-ray powder diffraction (XRD). Owing to the introduction of ionic liquid [BMIM] PF₆ and the synthetic effect on transition metal copper and ionic liquid [BMIM] PF₆, Cu-PF₆-MOF has the higher conductivity, larger electroactive surface area and better intrinsic catalytic properties of the skeletal transition metal, exhibiting enhanced electrocatalytic response to the reduction of paracetamol. The stable reduction peak at -104 mV was used as the ratiometric signal for analytical paracetamol detection using differential pulse voltammetry (DPV), with a linear range of 0.1-100 μM and a detection limit of 0.03 μM (S/N = 3). In addition, the constructed sensor showed good reproducibility, stability and interference resistance, as well as ideal recoveries (98.20%-104.40%) for the analysis of paracetamol in water samples.

Keywords: Differential pulse voltammetry; Ionic liquid; Paracetamol; Self-built ratiometric sensor; Transition metal copper; Water samples detection.