Arsenic as hazardous pollutant: Perspectives on engineering remediation tools

Abstract

Arsenic (As) is highly toxic metal (loid) that impairs plant growth and proves fatal towards human population. It disrupts physiological, biochemical and molecular attributes of plants associated with water/nutrient uptake, redox homeostasis, photosynthetic machineries, cell/membrane damage, and ATP synthesis. Numerous transcription factors are responsive towards As through regulating stress signaling, toxicity and resistance. Additionally, characterization of specific genes encoding uptake, translocation, detoxification and sequestration has also explained their underlying mechanisms. Arsenic within soil enters the food chain and cause As-poisoning. Plethora of conventional methods has been used since decades to plummet As-toxicity, but the success rate is quite low due to environmental hazards. Henceforth, exploration of effective and eco-friendly methods is aimed for As-remediation. With the technological advancements, we have enumerated novel strategies to address this concern for practicing such techniques on global scale. Novel strategies such as bioremediation, phytoremediation, mycorrhizae-mediated remediation, biochar, algal-remediation etc. possess extraordinary results. Moreover, nitric oxide (NO), a signaling molecule has also been explored in relieving As-stress through reducing oxidative damages and triggering antioxidative responses. Other strategies such as role of plant hormones (salicylic acid, indole-3-acetic acid, jasmonic acid) and micro-nutrients such as selenium have also been elucidated in As-remediation from soil. This has been observed through stimulated antioxidant activities, gene expression of transporters, defense genes, cell-wall modifications along with the synthesis of chelating agents such as phytochelatins and metallothioneins. This review encompasses the updated information about As toxicity and its remediation through novel techniques that serve to be the hallmarks for stress revival. We have summarised the genetic engineering protocols, biotechnological as well as nanotechnological applications in plants to combat As-toxicity.

Keywords: Arsenic toxicity; Biotechnological aspects; Microbial remediation; Nanotechnology; Speciation; Transporters.