OSAS Severity and Occlusal Parameters: A Prospective Study among Adult Subjects with Comorbidities

Int J Environ Res Public Health. 2022 May 1;19(9):5517. doi: 10.3390/ijerph19095517.

Abstract

Introduction: OSAS is an emerging public health problem. Early diagnosis in adults with comorbidities is the gold standard to avoid complications caused by a late diagnosis. The aim of the study, part of the SLeeP@SA project, was to identify within a population with dysmetabolic comorbidities the association of occlusal clinical signs, defined by orthodontic parameters, and of the anthropometric phenotype, with the severity of OSAS.

Materials and methods: A dedicated questionnaire containing questions regarding the presence of deep bite, augmented overjet, partial edentulism, and bruxism was completed by clinic staff. OSAS was evaluated using an unattended home PSG device, which recorded the AHI value. BMI and neck circumference were also measured. The Kolmogorov-Smirnov test was performed to evaluate the association of the AHI with occlusal clinical signs. The significance was set at p ≤ 0.05. The association of AHI with BMI and neck circumference was evaluated with the Pearson correlation coefficient.

Results: In total, 199 subjects were evaluated. No statistically significant association between occlusal parameters and AHI was found, while the AHI showed a positive correlation with BMI and neck circumference. The neck circumference seemed to be a better clinical predictor for OSAS severity than BMI, especially for females.

Conclusions: These results highlight how the orthodontic clinical data alone are not sufficient to establish an association between occlusal anomalies and OSAS severity, but further investigation involving a specialist orthodontic diagnosis is necessary.

Keywords: OSAS; apnea; breathing; comorbidities; obstructive sleep; sleep disorder.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Comorbidity
  • Female
  • Humans
  • Polysomnography / methods
  • Prospective Studies
  • Severity of Illness Index
  • Sleep
  • Sleep Apnea, Obstructive* / diagnosis

Grants and funding

This research was funded by INAIL, Progetto BRIC Inail 2018 ID 04/2018 SLeeP@SA—Salute sul Lavoro e Prevenzione delle Obstructive Sleep Apnea: un’epidemia silenziosa and the APC was funded by Department of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, Rome, Italy.