RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies

Bioinformatics. 2022 Jun 13;38(12):3304-3305. doi: 10.1093/bioinformatics/btac317.

Abstract

Motivation: Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level.

Results: We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies.

Availability and implementation: https://github.com/rcsb/rcsb-saguaro-3d.

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Databases, Protein
  • Macromolecular Substances / chemistry
  • Nucleic Acids*
  • Proteins / chemistry
  • Software*

Substances

  • Macromolecular Substances
  • Proteins
  • Nucleic Acids