Functionalization of halloysite nanotubes by enlargement and layer-by-layer assembly for controlled release of the fungicide iodopropynyl butylcarbamate

Xiaobei Jin; Rong Zhang; Minglei Su; Huairui Li; Xianfeng Yue; Daochun Qin; Zehui Jiang

doi:10.1039/c9ra07593c

Functionalization of halloysite nanotubes by enlargement and layer-by-layer assembly for controlled release of the fungicide iodopropynyl butylcarbamate

RSC Adv. 2019 Dec 18;9(72):42062-42070. doi: 10.1039/c9ra07593c.

Authors

Xiaobei Jin¹, Rong Zhang¹, Minglei Su¹, Huairui Li¹, Xianfeng Yue¹, Daochun Qin¹, Zehui Jiang¹

Affiliation

¹ International Centre for Bamboo and Rattan No. 8, Futong East Street, Chaoyang District Beijing PR China qindc@icbr.ac.cn jiangzehui@icbr.ac.cn.

Abstract

Iodopropynyl butylcarbamate (IPBC) is currently one of the most important fungicides widely used for industrial coatings and bamboo treatment. In this work, a controlled release composite with IPBC for inhibition of mold and stain fungi was prepared using enlarged halloysite nanotubes (HNTs) with layer-by-layer (LbL) assembly of polyelectrolyte multilayers. The acid-treated HNTs retained their tubular structure with increased internal diameter, and IPBC loading efficiency was therefore increased to 24.4%, approximately three times the amount of raw HNTs (8.4%). In vitro drug release assay showed that IPBC could be released from HNTs in a sustainable manner with a total release amount of 33.8% over a period of 35 days. The release rate of IPBC could be further controlled by adjusting the number of LbL layers on the tubes and the released amount of IPBC could be limited to less than 10% in 100 days. An inhibition zone test indicated the as-prepared nanocomposites exhibited significant anti-fungal performance against three mold fungi (Aspergillus niger, Trichoderma viride, and Penicillium citrinum) and one stain fungus (Botryodiplodia theobromae). The results support the potential use of HNTs for a prolonged service life of bamboo products.