Keywords: BCL10, B-cell lymphoma/leukemia 10; CARD9; CARD9, caspase-recruitment domain 9 protein; CVDs, cardiovascular diseases; CXCL, CXC-chemokine ligand; GDI, GDP-dissociation inhibitors; I/R, ischemia/reperfusion; IFN, interferon; MAPK, mitogen-activated protein kinase; MCP, monocyte chemoattractant protein; NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells; ROS, reactive oxygen species; TGF, transforming growth factor; TNF, tumor necrosis factor; autophagy; cardiovascular disease; cytokines; oxidative stress.