Anti-inflammatory effect of siRNAs targeted il-4 and il-13 in a mouse model of allergic rhinitis

Allergy. 2022 Sep;77(9):2829-2832. doi: 10.1111/all.15366. Epub 2022 May 22.

Authors

Igor Shilovskiy¹, Alexandra Nikonova^{1

2}, Ekaterina Barvinskaia¹, Mariya Kaganova¹, Aleksandr Nikolskii¹, Lyudmila Vishnyakova¹, Valeriia Kovchina¹, Kirill Yumashev¹, Artem Korneev¹, Olga Petukhova¹, Dmitry Kudlay^{1

3}, Valeriy Smirnov^{1

3}, Sergey Andreev¹, Ksenia Kozhikhova¹, Artem Shatilov¹, Anastasiia Shatilova¹, Artem Maerle¹, Ilya Sergeev¹, Dmitry Trofimov¹, Musa Khaitov^{1

4}

Affiliations

¹ NRC Institute of Immunology FMBA, Moscow, Russia.
² RUDN University, Moscow, Russia.
³ I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
⁴ Pirogov Russian National Research Medical University, Moscow, Russia.

PMID: 35538848
DOI: 10.1111/all.15366

No abstract available

Keywords: Allergic rhinitis; IL-13; IL-4; cytokines; siRNA.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Inflammatory Agents / pharmacology
Cytokines / pharmacology
Disease Models, Animal
Mice
Mice, Inbred BALB C
Nasal Mucosa
RNA, Small Interfering / genetics
RNA, Small Interfering / pharmacology
Rhinitis, Allergic* / drug therapy

Substances

Anti-Inflammatory Agents
Cytokines
RNA, Small Interfering