Melanoma in skin of color: Part I. Epidemiology and clinical presentation

J Am Acad Dermatol. 2023 Sep;89(3):445-456. doi: 10.1016/j.jaad.2022.04.056. Epub 2022 May 6.

Abstract

Although there is a higher incidence of melanoma among non-Hispanic White individuals, melanoma is diagnosed at more advanced stages and associated with worse survival rates among individuals with skin of color (SOC). The proportions of melanoma subtypes differ across racial groups, with acral lentiginous melanoma and mucosal melanoma representing higher proportions of melanoma diagnoses in individuals with SOC compared to White individuals. The recognition of distinct differences in anatomic locations and dermatoscopic patterns may facilitate the appropriate differentiation of physiologic from pathologic pigmentation. The first article of this continuing medical education series will focus on the epidemiology and clinical presentation of melanoma in individuals with SOC, with the aim of improving early diagnoses and clinical outcomes.

Keywords: acral lentiginous melanoma; dermatoscopy; epidemiology; melanoma; melanonychia; mucosal melanoma; racial disparity; skin of color.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Dermoscopy
  • Humans
  • Melanoma* / diagnosis
  • Melanoma* / epidemiology
  • Melanoma* / pathology
  • Skin / pathology
  • Skin Neoplasms* / diagnosis
  • Skin Neoplasms* / epidemiology
  • Skin Neoplasms* / pathology
  • Skin Pigmentation