Obesity is an important risk factor for chronic kidney disease. Bariatric surgery (BS) may improve long-term kidney outcomes, but there is no agreement regarding the benefit and timing of BS in patients with end-stage renal disease. We present a 46-year-old male patient with type 2 diabetes mellitus, in hemodialysis (HD), and with a body mass index (BMI) of 39.79 kg/m2, who was submitted to laparoscopic one-anastomosis gastric bypass surgery. Eight months after surgery, and after a 40-kg weight loss, the patient showed signs of kidney function improvement and HD was discontinued. At this moment, one year after, the patient has an estimated glomerular filtration rate of 21.2 mL/min/1.73 m2 and a BMI of 25.61 kg/m2. To our knowledge, this case report seems to be the first one to talk about a HD patient that improved kidney function enough to stop dialysis.