Stroke-mimicking unilateral hypokalemic paralysis and literature review

Am J Emerg Med. 2022 Aug:58:349.e1-349.e3. doi: 10.1016/j.ajem.2022.04.042. Epub 2022 Apr 30.

Abstract

Unilateral paralysis is an alarming symptom with broad differential diagnoses, including stroke, Todd's paralysis, myelopathy, and peripheral neuropathy. Hypokalemic paralysis (HP), a neuromuscular disorder associated with muscle dysfunction, is caused by hypokalemia and manifests as symmetric proximal extremity muscle weakness. Unilateral paralysis has rarely been reported in the literature. Once hypokalemia is corrected, HP is usually reversible. Delayed diagnosis and treatment may result in fatal consequences. Here, we report an atypical case of unilateral weakness along with a review of the literature on unilateral HP.

Keywords: Hypokalemia; Hypokalemic paralysis; Stroke mimic; Unilateral paralysis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Humans
  • Hypokalemia* / complications
  • Hypokalemia* / etiology
  • Hypokalemic Periodic Paralysis* / diagnosis
  • Hypokalemic Periodic Paralysis* / etiology
  • Muscle Weakness / etiology
  • Paralysis / diagnosis
  • Paralysis / etiology
  • Stroke* / complications
  • Stroke* / diagnosis