An Infant With Interstitial Lung Disease of Rare Cause

Chest. 2022 May;161(5):e273-e278. doi: 10.1016/j.chest.2021.12.639.

Abstract

An 11-month-old boy was admitted to our hospital because of "recurrent cough with intermittent dyspnea for more than 8 months, aggravated for 1 month." The baby began experiencing a recurrent milk-choking problem within 1.5 months after birth. He had been hospitalized four times, but the symptoms recurred. One month previously, the symptoms were aggravated and a chest CT scan performed at outside hospital showed interstitial changes. Pediatric bronchoscopy revealed bronchial inflammatory features, with hemosiderin-laden macrophages being found in BAL fluid (BALF). Also, periodic acid-Schiff (PAS) staining showed positive results, which indicated the possibility of pulmonary alveolar proteinosis (PAP) or idiopathic pulmonary hemosiderosis (IPH).

Publication types

  • Case Reports

MeSH terms

  • Bronchoscopy
  • Child
  • Hemosiderosis* / diagnosis
  • Humans
  • Infant
  • Lung Diseases* / diagnosis
  • Lung Diseases, Interstitial* / complications
  • Lung Diseases, Interstitial* / diagnosis
  • Male
  • Pulmonary Alveolar Proteinosis* / diagnosis
  • Pulmonary Alveolar Proteinosis* / diagnostic imaging
  • Tomography, X-Ray Computed