Studying of Molecular Regulation of Developmental Processes of Lower Metazoans Exemplified by Cnidaria Using High-Throughput Sequencing

Biochemistry (Mosc). 2022 Mar;87(3):269-293. doi: 10.1134/S0006297922030075.

Abstract

A unique set of features and characteristics of species of the Cnidaria phylum is the one reason that makes them a model for a various studies. The plasticity of a life cycle and the processes of cell differentiation and development of an integral multicellular organism associated with it are of a specific scientific interest. A new stage of development of molecular genetic methods, including methods for high-throughput genome, transcriptome, and epigenome sequencing, both at the level of the whole organism and at the level of individual cells, makes it possible to obtain a detailed picture of the development of these animals. This review examines some modern approaches and advances in the reconstruction of the processes of ontogenesis of cnidarians by studying the regulatory signal transduction pathways and their interactions.

Keywords: Cnidaria; development; genomics; sequencing technologies; signaling pathways.

Publication types

  • Review

MeSH terms

  • Animals
  • Cnidaria* / genetics
  • Cnidaria* / metabolism
  • Genome
  • High-Throughput Nucleotide Sequencing
  • Signal Transduction
  • Transcriptome