Malignant lymphoma of the lower urinary tract: A single institutional experience

Pathol Res Pract. 2022 Jun:234:153932. doi: 10.1016/j.prp.2022.153932. Epub 2022 Apr 29.

Abstract

Lymphoma of the urinary tract is relatively rare and comprises of < 5% of all primary extra nodal lymphoma. Diagnoses of these lesions at anearly stage is important as they can disseminate or transform into high grade lesion if there is a delay in the diagnoses. There are only few case series and case reports on the malignant lymphoma of the urinary tract. The aim of this study was to characterize lymphoma involving the urinary bladder and prostate. We retrospectively reviewed the clinical data and histologic findings of the malignant lymphoma involving urinary bladder and prostate at our institution. Lymphoma involving the lower urinary tract clinically presented with lower urinary tract symptoms and usually with concurrent associated urinary bladder cancer or prostatic cancer in our series. Lymphoma should be included in the differential diagnoses especially in patients with prior history of lymphoid disorders. There should be a high index of suspicion when there is any atypical lymphoid infiltrate in routine urinary bladder and prostate surgical specimens.

Keywords: Genitourinary lymphoma; Malignant lymphoma; Prostate; Urinary bladder.

MeSH terms

  • Humans
  • Lymphoma* / diagnosis
  • Lymphoma* / pathology
  • Male
  • Prostate / pathology
  • Prostatic Neoplasms* / pathology
  • Retrospective Studies
  • Urinary Bladder / pathology
  • Urinary Bladder Neoplasms* / pathology