Renal artery thrombosis in SARS-CoV-2 infection: a case report

BMC Nephrol. 2022 May 6;23(1):175. doi: 10.1186/s12882-022-02808-5.

Abstract

Background: Coronavirus disease 2019 (COVID-19) is identified as the pneumonia and acute respiratory distress syndrome caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). The intravascular thrombotic phenomena related to the COVID-19 are emerging as an important complication that contribute to significant mortality.

Case presentation: We present a 62-year-old man with severe COVID-19 and type 2 diabetes. After symptomatic and supportive treatment, the respiratory function was gradually improved. However, the patient suddenly developed abdominal pain, and the enhanced CT scan revealed renal artery thrombosis. Given the risk of surgery and the duration of the disease, clopidogrel and heparin sodium were included in the subsequent treatment. The patient recovered and remained stable upon follow-up.

Conclusions: Thrombosis is at a high risk in patients with severe COVID-19 pneumonia because of hypercoagulable state, blood stasis and endothelial injury. Thrombotic events caused by hypercoagulation status secondary to vascular endothelial injury deserves our attention. Because timely anticoagulation can reduce the risk of early complications, as illustrated in this case report.

Keywords: 2019 novel coronavirus disease; Hypercoagulability; Renal artery thrombosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19* / complications
  • Diabetes Mellitus, Type 2* / complications
  • Humans
  • Male
  • Middle Aged
  • RNA, Viral
  • Renal Artery / diagnostic imaging
  • SARS-CoV-2
  • Thrombophilia*
  • Thrombosis* / diagnostic imaging
  • Thrombosis* / etiology

Substances

  • RNA, Viral