Updates in Molecular Breast Imaging

Semin Roentgenol. 2022 Apr;57(2):134-138. doi: 10.1053/j.ro.2021.12.006. Epub 2021 Dec 31.

Abstract

Molecular breast imaging (MBI) is a nuclear medicine study performed with dedicated gamma camera systems optimized to image the uptake of Tc-99m sestamibi in the breast. MBI provides a relatively low-cost and simple functional breast imaging method that can identify breast cancers obscured by dense fibroglandular tissue on mammography. Recent studies have also found that background levels of uptake in benign dense tissue may provide breast cancer risk information. This article discusses the latest updates in MBI technology, recent evidence supporting its clinical use, and work in progress that may aid in wider adoption of MBI.

MeSH terms

  • Breast Neoplasms* / diagnostic imaging
  • Breast* / diagnostic imaging
  • Female
  • Gamma Cameras
  • Humans
  • Mammography / methods
  • Molecular Imaging / methods
  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi

Substances

  • Radiopharmaceuticals
  • Technetium Tc 99m Sestamibi