A dopamine electrochemical sensor based on a platinum-silver graphene nanocomposite modified electrode

Nadzirah Sofia Anuar; Wan Jeffrey Basirun; Md Shalauddin; Shamima Akhter

doi:10.1039/c9ra11056a

A dopamine electrochemical sensor based on a platinum-silver graphene nanocomposite modified electrode

RSC Adv. 2020 May 5;10(29):17336-17344. doi: 10.1039/c9ra11056a. eCollection 2020 Apr 29.

Authors

Nadzirah Sofia Anuar¹, Wan Jeffrey Basirun^{1

2}, Md Shalauddin^{1

2}, Shamima Akhter¹

Affiliations

¹ Department of Chemistry, Faculty of Science, University of Malaya Kuala Lumpur 50603 Malaysia sofiazira92@gmail.com jeff@um.edu.my +603 7967 4193 +603 7967 4082.
² Institute of Nanotechnology and Catalysis (NanoCat), University of Malaya Kuala Lumpur 50603 Malaysia.

Abstract

A platinum-silver graphene (Pt-Ag/Gr) nanocomposite modified electrode was fabricated for the electrochemical detection of dopamine (DA). Electrochemical studies of the Pt-Ag/Gr nanocomposite towards DA detection were performed by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The CV analysis showed that Pt-Ag/Gr/GCE had enhanced electrocatalytic activity towards DA oxidation due to the synergistic effects between the platinum-silver nanoparticles and graphene. The DPV results showed that the modified sensor demonstrated a linear concentration range between 0.1 and 60 μM with a limit of detection of 0.012 μM. The Pt-Ag/Gr/GCE presented satisfactory results for reproducibility, stability and selectivity. The prepared sensor also showed acceptable recoveries for a real sample study.