Kounis syndrome following COVID-19 vaccination

Chadi Allam; Nicholas G Kounis; Roy Chlawit; Marc Saouma; Georges Badaoui

doi:10.1080/08998280.2022.2034226

Kounis syndrome following COVID-19 vaccination

Proc (Bayl Univ Med Cent). 2022 Mar 9;35(3):369-370. doi: 10.1080/08998280.2022.2034226. eCollection 2022.

Authors

Chadi Allam^{1

2}, Nicholas G Kounis³, Roy Chlawit^{1

2}, Marc Saouma^{1

2}, Georges Badaoui^{1

2}

Affiliations

¹ Faculty of Medicine, Saint-Joseph University, Beirut, Lebanon.
² Department of Cardiology, Hôtel-Dieu de France Hospital, Beirut, Lebanon.
³ Department of Internal Medicine, Division of Cardiology, University of Patras Medical School, Patras, Greece.

Abstract

Coronary stent thrombosis is a life-threatening condition induced by multiple factors, including allergic reactions. A 64-year-old man presented with stent thrombosis in the left anterior descending artery and multiple cardiorespiratory arrests immediately after the first dose of the BNT162b1 mRNA vaccine. He underwent emergent percutaneous coronary intervention. Anaphylaxis-induced stent thrombosis, or type III Kounis syndrome, is a highly possible diagnosis. Cardiogenic shock can hide the skin manifestations of anaphylaxis, making this syndrome challenging to diagnose. This clinical case underscores the importance of surveillance for at least 30 minutes after vaccine administration, especially in patients at risk.

Keywords: Anaphylaxis; COVID-19; Kounis syndrome; myocardial infarction; stent thrombosis; vaccine.

Publication types

Case Reports