We describe persistent circulation of SARS-CoV-2 Alpha variant in an immunosuppressed patient in France during February 2022. The virus had a new pattern of mutation accumulation. The ongoing circulation of previous variants of concern could lead to reemergence of variants with the potential to propagate future waves of infection.
Keywords: Alpha variant; COVID-19; France; SARS; SARS-CoV-2; coronavirus; coronavirus disease; mutations; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.