Brain-behavior correlations: Two paths toward reliability

Caterina Gratton; Steven M Nelson; Evan M Gordon

doi:10.1016/j.neuron.2022.04.018

Brain-behavior correlations: Two paths toward reliability

Neuron. 2022 May 4;110(9):1446-1449. doi: 10.1016/j.neuron.2022.04.018.

Authors

Caterina Gratton¹, Steven M Nelson², Evan M Gordon³

Affiliations

¹ Department of Psychology, Northwestern University, Evanston, IL, USA; Department of Neurology, Northwestern University, Evanston, IL, USA. Electronic address: caterina.gratton@gmail.com.
² Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA; Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
³ Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.

PMID: 35512638
DOI: 10.1016/j.neuron.2022.04.018

Abstract

In a recent issue of Nature, Marek et al. (2022) demonstrate that cross-sectional brain-behavior correlations are often small and unreliable without large samples. This observation pushes human neuroscience toward study designs that either maximize sample sizes to detect small effects or maximize effect sizes using focused investigations.

Publication types

Comment

MeSH terms

Brain*
Cross-Sectional Studies
Humans
Neurosciences*
Reproducibility of Results
Sample Size

Abstract

Publication types

MeSH terms

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