Research progress on postoperative transient neurological dysfunction in pediatric and adult patients with moyamoya disease after revascularization surgery

Abstract

Moyamoya disease (MMD) is characterized by occlusion of the internal carotid artery (ICA) and its terminal branches, leading to compromised cerebral perfusion. Surgical revascularization is an effective therapy to improve cerebral hemodynamic. Transient neurological dysfunction (TND) usually occurs early after surgery and resolved within a few weeks without permanent neurologic deficit. In this article, we have reviewed the clinical features, mechanisms, and factors about TND in both pediatric and adult MMD patient.

Keywords: Cerebral hyperperfusion syndromes; Hemodynamic; Moyamoya disease; Revascularization surgery; Transient neurological dysfunction.