Review of recent evidence on the management of heartburn in pregnant and breastfeeding women

BMC Gastroenterol. 2022 May 4;22(1):219. doi: 10.1186/s12876-022-02287-w.

Abstract

Gastroesophageal reflux disease (GERD) is one the most common medical complaints in pregnant women. Some women continue to experience GERD symptoms after delivery. Effective management of GERD symptoms is important to improve productivity and quality of life. Management of heartburn in pregnant and breastfeeding women involves lifestyle modifications, dietary modifications, non-pharmaceutical remedies and pharmaceutical drugs. For most patients, lifestyle/dietary modifications are helpful in reducing GERD symptoms. For patients who require a more intense intervention, various types of pharmaceutical drugs are available. However, the suitability of each treatment for use during pregnancy and lactation must be taken into consideration. This article explores the reported efficacy and safety of these treatment options in pregnant and breastfeeding women. Recommended treatment algorithm in pregnant and breastfeeding women have been developed.

Keywords: Breastfeeding; Gastroesophageal reflux disease; Heartburn; Pregnancy; Treatment.

Publication types

  • Review

MeSH terms

  • Breast Feeding
  • Female
  • Gastroesophageal Reflux* / drug therapy
  • Heartburn / drug therapy
  • Heartburn / therapy
  • Humans
  • Pharmaceutical Preparations
  • Pregnancy
  • Pregnancy Complications* / therapy
  • Quality of Life

Substances

  • Pharmaceutical Preparations