Spinal cord protection in open and endovascular approaches to thoracoabdominal aortic aneurysms

Vascular. 2023 Oct;31(5):874-883. doi: 10.1177/17085381221094411. Epub 2022 May 4.

Abstract

Despite advancements in surgical and postoperative management, spinal cord injury has been a persistent complication of both open and endovascular repair of thoracoabdominal and descending thoracic aortic aneurysm. Spinal cord injury can be explained with an ischemia-infarction model which results in local edema of the spinal cord, damaging its structure and leading to reversible or irreversible loss of its function. Perfusion of the spinal cord during aortic procedures can be enhanced by several adjuncts which have been described with a broad variety of evidence in their support. These adjuncts include systemic hypothermia, cerebrospinal fluid drainage, extracorporeal circulation and distal aortic perfusion, segmental arteries reimplantation, left subclavian artery revascularization, and staged aortic repair. The Authors here reviewed and discussed the role of such adjuncts in preventing spinal cord injury from occurring, pinpointing current evidence and outlining future perspectives.

Keywords: Spinal cord; aneurysm; aortic; protection; surgery; thoracic endovascular aortic aneurysm repair.

Publication types

  • Review

MeSH terms

  • Aortic Aneurysm, Abdominal* / complications
  • Aortic Aneurysm, Thoracic* / complications
  • Aortic Aneurysm, Thoracic* / diagnostic imaging
  • Aortic Aneurysm, Thoracic* / surgery
  • Aortic Aneurysm, Thoracoabdominal*
  • Endovascular Procedures* / adverse effects
  • Humans
  • Spinal Cord / blood supply
  • Spinal Cord Injuries* / complications
  • Spinal Cord Injuries* / prevention & control
  • Spinal Cord Ischemia* / etiology
  • Spinal Cord Ischemia* / prevention & control
  • Treatment Outcome