How to Study the Brain While Anesthetizing It?! A Scoping Review on Running Neuroanesthesiologic Studies and Trials That Include Neurosurgical Patients

Markus Klimek; Benjamin Y Gravesteijn; Andreia M Costa; Francisco A Lobo

doi:10.1016/j.wneu.2021.08.069

How to Study the Brain While Anesthetizing It?! A Scoping Review on Running Neuroanesthesiologic Studies and Trials That Include Neurosurgical Patients

World Neurosurg. 2022 May:161:376-381. doi: 10.1016/j.wneu.2021.08.069.

Authors

Markus Klimek¹, Benjamin Y Gravesteijn², Andreia M Costa³, Francisco A Lobo⁴

Affiliations

¹ Department of Anesthesiology, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address: M.Klimek@erasmusmc.nl.
² Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.
³ Department of Anesthesiology, Centro Hospitalar Lisboa Norte, Lisbon, Portugal.
⁴ Institute of Anesthesiology, Cleveland Clinic, Abu Dhabi, United Arabic Emirates.

PMID: 35505557
DOI: 10.1016/j.wneu.2021.08.069

Abstract

This scoping review addresses the challenges of neuroanesthesiologic research: the population, the methods/treatment/exposure, and the outcome/results. These challenges are put into the context of a future research agenda for peri-/intraoperative anesthetic management, neurocritical care, and applied neurosciences. Finally, the opportunities of adaptive trial design in neuroanesthesiologic research are discussed.

Keywords: Adaptive trial design; Applied neurosciences; Neuroanesthesia; Neurocritical care.

Publication types

Review

MeSH terms

Anesthetics* / therapeutic use
Brain / surgery
Humans
Neurosciences*
Research Design
Running*

Substances

Anesthetics