Spontaneous closure of an isolated congenital perimembranous ventricular septal defect in two dogs

BMC Vet Res. 2022 May 3;18(1):162. doi: 10.1186/s12917-022-03266-9.

Abstract

Background: Though spontaneous closure of isolated congenital ventricular septal defects in humans is very common, it has been rarely reported in dogs.

Case presentation: A 4 month old Havanese dog and a 4.5 month old Chihuahua x Jack Russell terrier cross were presented for murmur evaluation to the authors' institution. Both puppies were clinically healthy and had a loud systolic murmur on the right hemithorax. Echocardiography in both dogs revealed a small, isolated, restrictive perimembranous congenital ventricular septal defect. No echocardiographic signs of left ventricular volume overload or pulmonary hypertension were present. Re-check auscultation in both dogs revealed the absence of a murmur, and echocardiography showed no flow through the interventricular septum. In the 9 kg Havanese dog and the 4 kg mixed breed dog, spontaneous closure occurred at 13-17 months and 12-30 months, respectively.

Conclusions: In both dogs the spontaneous closure of a congenital perimembranous ventricular septal defect took place in a young adult age. The mechanism of closure remains unclear.

Keywords: Echocardiography; Natural history; Puppies; Screening.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Dog Diseases* / diagnostic imaging
  • Dogs
  • Echocardiography / veterinary
  • Heart Septal Defects, Ventricular* / diagnostic imaging
  • Heart Septal Defects, Ventricular* / veterinary
  • Heart Ventricles / diagnostic imaging