Forensic age assessment by 3.0 T MRI of the wrist: adaption of the Vieth classification

Eur Radiol. 2022 Nov;32(11):7956-7964. doi: 10.1007/s00330-022-08819-y. Epub 2022 May 4.

Abstract

Objectives: In order to find a reliable method to correctly assess majority in both sexes by MRI, a study was conducted to evaluate the applicability of the recently presented Vieth classification in wrist MRI, after it had originally been proposed for knee MRI.

Methods: After receiving a positive vote by the ethics committee, the left-hand wrists of 347 male and 348 female volunteers of German nationality in the age bracket 12-24 years were scanned. Before conducting the prospective, cross-sectional examinations, an informed consent was obtained from each volunteer. A 3.0 T MRI scanner was used, acquiring a T1 turbo spin-echo sequence (TSE) and a T2 TSE sequence with fat suppression by spectral presaturation with inversion recovery (SPIR). The images were assessed by applying the Vieth classification. Minimum, maximum, mean ± standard deviation, and median with lower and upper quartiles were defined. Intra- and interobserver agreements were determined by calculating the kappa coefficients. Differences between the sexes were analyzed using the Mann-Whitney U test.

Results: By applying the unmodified Vieth classification with corresponding schematics, it was possible to assess majority in both sexes via the epiphyseal-diaphyseal fusion of the distal radius and in males also via the epiphyseal-diaphyseal fusion of the distal ulna. The Mann-Whitney U test implied significant sex-related differences for all stages. For both epiphyses, the intra- and interobserver agreement levels were very good (κ > 0.8).

Conclusion: If confirmed by further studies, it would be possible to determine the completion of the 18th year of life in both sexes by 3.0 T MRI of the wrist and using the Vieth classification.

Key points: • The Vieth classification allows determining majority in males and females alike based on the distal radius' epiphysis by 3.0 T MRI of the wrist. • The Vieth classification also allows determining majority in males based on the distal ulna's epiphysis by 3.0 T MRI of the wrist, but not in females. • The presented data can be deemed referential within certain discussed boundaries.

Keywords: Age determination by skeleton; Magnetic resonance imaging; Radius; Ulna; Wrist.

MeSH terms

  • Adolescent
  • Adult
  • Age Determination by Skeleton* / methods
  • Child
  • Cross-Sectional Studies
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Osteogenesis
  • Prospective Studies
  • Wrist* / diagnostic imaging
  • Young Adult