Noncoding RNA as Diagnostic and Prognostic Biomarkers in Cerebrovascular Disease

Oxid Med Cell Longev. 2022 Apr 19:2022:8149701. doi: 10.1155/2022/8149701. eCollection 2022.

Abstract

Noncoding RNAs (ncRNAs), such as microRNAs, long noncoding RNAs, and circular RNAs, play an important role in the pathophysiology of cerebrovascular diseases (CVDs). They are effectively detectable in body fluids, potentially suggesting new biomarkers for the early detection and prognosis of CVDs. In this review, the physiological functions of circulating ncRNAs and their potential role as diagnostic and prognostic markers in patients with cerebrovascular diseases are discussed, especially in acute ischemic stroke, subarachnoid hemorrhage, and moyamoya disease.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Cerebrovascular Disorders* / diagnosis
  • Cerebrovascular Disorders* / genetics
  • Humans
  • Ischemic Stroke*
  • Prognosis
  • RNA, Untranslated / genetics

Substances

  • Biomarkers
  • RNA, Untranslated