Annulus-shaped I-125 plaque brachytherapy for conjunctival melanoma

Sean T Berkowitz; Anderson L Brock; Melvin A Astrahan; David A Reichstein

doi:10.1016/j.ajoc.2022.101512

Annulus-shaped I-125 plaque brachytherapy for conjunctival melanoma

Am J Ophthalmol Case Rep. 2022 Apr 18:26:101512. doi: 10.1016/j.ajoc.2022.101512. eCollection 2022 Jun.

Authors

Sean T Berkowitz¹, Anderson L Brock², Melvin A Astrahan³, David A Reichstein²

Affiliations

¹ Vanderbilt University Medical Center, USA.
² Tennessee Retina, Nashville, TN, USA.
³ Department of Radiation Oncology, University of Southern California School of Medicine, Los Angeles, CA, USA.

Abstract

Purpose: To report successful ring-shaped iodine-125 plaque brachytherapy for conjunctival melanoma.

Observations: Eye Physics (EP) plaque brachytherapy, designed with Plaque Simulator software, proved to be an effective treatment modality with some corneal irritation and no recurrence at 12-months post radiation.

Conclusion and importance: Management of conjunctival melanoma is complicated by the lack of gold standard adjuvant treatments. I-125 EP plaque brachytherapy represents a viable option for these malignancies. Specifically, ring-shaped plaque geometries allow for targeted radiotherapy.

Keywords: Annular plaque; Conjunctival melanoma; I-125; Plaque brachytherapy.

Publication types

Case Reports