Targeted epidural blood patch through a catheter in the treatment of spontaneous intracranial hypotension

Clin Neurol Neurosurg. 2022 Jun:217:107268. doi: 10.1016/j.clineuro.2022.107268. Epub 2022 Apr 26.

Abstract

Objective: Spontaneous intracranial hypotension (SIH) can be effectively treated by epidural blood patch (EBP) following the primary unsuccessful conservative therapy. Nevertheless, multi-site cerebrospinal fluid (CSF) leaks or those originating at the cervical or thoracic spine remain therapeutically challenging. Therefore, this study aimed to present our experience in the treatment of thoracic CSF leaks using epidural catheters for the EBP infusion.

Methods: Three patients presenting with typical orthostatic headaches were qualified for an EBP procedure. Preoperative MRI scans, myelography, and CT myelography were performed. Additionally, delayed CT myelography was repeated after 3 h to identify the CSF leakage site. Patients were followed-up clinically and radiologically for three months.

Results: The CT myelography identified CSF leak at the T2-3 (case 1), T5-12 (case 2), and T3-7 level (Case 3). A 0.06" diameter lumbar drainage catheter (Case 1 and 2) or Abbot's spinal cord stimulation (SCS) catheter (Case 3) was inserted epidurally through the lower thoracic/lumbar single-entry point and advanced into the identified thoracic leak site. The average volume of injected blood was 15.7 ml. No procedure-related complications were observed, and all patients improved clinically.

Conclusions: Epidural catheters remain safe and effective in treating thoracic and multi-site CSF leaks. In addition, Abbot's SCS catheter was found superior to the lumbar drainage catheter due to higher rigidity and bigger diameter despite being shorter than the lumbar drainage catheter.

Keywords: Epidural blood patch; Epidural catheter; Headaches; Myelography; Spontaneous intracranial hypotension; Technical note.

MeSH terms

  • Blood Patch, Epidural* / adverse effects
  • Blood Patch, Epidural* / methods
  • Catheters / adverse effects
  • Cerebrospinal Fluid Leak / etiology
  • Humans
  • Intracranial Hypotension* / complications
  • Intracranial Hypotension* / diagnostic imaging
  • Intracranial Hypotension* / therapy
  • Magnetic Resonance Imaging / adverse effects
  • Myelography / adverse effects