Neurofilament assessment in patients with cervical dystonia

Gina Ferrazzano; Maria Antonella Zingaropoli; Matteo Costanzo; Daniele Belvisi; Federica Dominelli; Patrizia Pasculli; Maria Rosa Ciardi; Giovanni Fabbrini; Giovanni Defazio; Alfredo Berardelli; Antonella Conte

doi:10.1016/j.parkreldis.2022.04.013

Neurofilament assessment in patients with cervical dystonia

Parkinsonism Relat Disord. 2022 May:98:70-71. doi: 10.1016/j.parkreldis.2022.04.013. Epub 2022 Apr 23.

Affiliations

¹ Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy.
² Department of Public Health and Infectious Diseases, Sapienza University of Rome, Viale del Policlinico 155, 00185, Rome, Italy.
³ IRCCS NEUROMED, Via Atinense 18, 86077, Pozzilli, Italy.
⁴ Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy; IRCCS NEUROMED, Via Atinense 18, 86077, Pozzilli, Italy.
⁵ Department of Medical Sciences and Public Health, University of Cagliari, SS 554 Bivio Sestu, 09042, Monserrato, CA, Italy.
⁶ Department of Human Neuroscience, Sapienza University of Rome, Viale dell'Università 30, 00185, Rome, Italy; IRCCS NEUROMED, Via Atinense 18, 86077, Pozzilli, Italy. Electronic address: antonella.conte@uniroma1.it.

PMID: 35487128
DOI: 10.1016/j.parkreldis.2022.04.013

Abstract

We evaluated levels of serum neurofilament light chains (NfL), a known biomarker of neuroaxonal damage, in patients with cervical dystonia (CD) and healthy controls (HCs). CD patients had normal NfL levels supporting the hypothesis that CD may be considered as a functional network disorder rather than as a neurodegenerative disease.

Publication types

Letter

MeSH terms

Biomarkers
Humans
Intermediate Filaments
Neurodegenerative Diseases*
Neurofilament Proteins
Torticollis*

Substances

Biomarkers
Neurofilament Proteins