New-onset lupus nephritis associated with COVID-19 infection

Brigitte Kazzi; Derek Fine; Duvuru Geetha; Melody Chung; Manny Monroy-Trujillo; Homa Timlin

doi:10.1177/09612033221098571

New-onset lupus nephritis associated with COVID-19 infection

Lupus. 2022 Jul;31(8):1007-1011. doi: 10.1177/09612033221098571. Epub 2022 Apr 29.

Authors

Brigitte Kazzi¹, Derek Fine², Duvuru Geetha¹, Melody Chung², Manny Monroy-Trujillo¹, Homa Timlin³

Affiliations

¹ 1466Johns Hopkins University, Baltimore, MD, USA.
² Johns Hopkins University School of Medicine, Baltimore, MD, USA.
³ Hopkins, Baltimore, MD, USA.

Abstract

A dysregulated immune response plays a critical role in systemic lupus erythematosus (SLE) pathogenesis. Environmental factors such as viruses, including coronavirus 2 (COVID-19), have been described to play a role in SLE presentation and exacerbation. These viruses trigger a host's humoral and cellular immunities typically essential in elimination of the viral infection. We present a case of a Hispanic male who developed new-onset lupus nephritis class II after a COVID-19 infection.

Keywords: COVID-19; lupus nephritis; systemic lupus erythematosus.

Publication types

Case Reports

MeSH terms

COVID-19* / complications
Humans
Lupus Erythematosus, Systemic* / complications
Lupus Erythematosus, Systemic* / diagnosis
Lupus Nephritis* / complications
Male