Review of electrochemical and optical biosensors for testosterone measurement

Biotechnol Appl Biochem. 2023 Feb;70(1):318-329. doi: 10.1002/bab.2354. Epub 2022 Jun 21.

Abstract

Testosterone is an anabolic steroid and a major sex hormone in males. It plays vital roles, including developing the testis, penis, and prostate, increasing muscle and bone, and sperm production. In both men and women, testosterone levels should be in normal ranges. Besides, testosterone and its analogs are major global contributors to doping in sport. Due to the importance of testosterone testing, novel, accurate biosensors have been developed. This review summarizes the various methods for testosterone measurement. Also, recent optical and electrochemical approaches for the detection of testosterone and its analogs have been discussed.

Keywords: biosensors; nanomaterials; nanotechnology; testosterone.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • Female
  • Humans
  • Male
  • Semen*
  • Testosterone

Substances

  • Testosterone