Comparison of Male and Female Sexual Dysfunction between Hemodialysis and Peritoneal Dialysis in Patients with End-Stage Renal Disease: An Analytical Cross-Sectional Study

Shahryar Zeighami; Saeid Dehghankhalili; Khadije Heiran; Seyede Pegah Azarchehry; Alireza Heiran; Mehrab Sayadi; Fatemeh Azadian

doi:10.1155/2022/9404025

Comparison of Male and Female Sexual Dysfunction between Hemodialysis and Peritoneal Dialysis in Patients with End-Stage Renal Disease: An Analytical Cross-Sectional Study

Int J Endocrinol. 2022 Apr 18:2022:9404025. doi: 10.1155/2022/9404025. eCollection 2022.

Authors

Shahryar Zeighami¹, Saeid Dehghankhalili², Khadije Heiran³, Seyede Pegah Azarchehry⁴, Alireza Heiran⁵, Mehrab Sayadi⁶, Fatemeh Azadian⁵

Affiliations

¹ Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran.
² Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
³ Department of Midwifery, School of Nursing and Midwifery, Zahedan University of Medical Sciences, Zahedan, Iran.
⁴ Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
⁵ Non-Communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
⁶ Cardiovascular Research Center, Mohammad Rasoolallah Research Tower, Shiraz University of Medical Sciences, Shiraz, Iran.

Abstract

Background: Maintenance dialysis is the most common treatment for end-stage renal disease (ESRD) patients. One of the most ignored but important health issue among dialysis patients is sexual dysfunction, which interferes with quality of life (QoL). Studies showed that the side effects of the two conventional methods of dialysis (hemodialysis (HD) and peritoneal dialysis (PD)) are different on a patient's health. Therefore, we sought to compare the sexual dysfunction score, both male and female, between patients undergoing HD and PD.

Methods: One hundred seventy adults (85 HD and 85 PD) subject with end-stage renal disease (ESRD) on dialysis for at least 2 months were included. For male subjects, the erectile function (EF) domain of the International Index of Erectile Function (IIEF) questionnaire was calculated. Moreover, the Female Sexual Function Index (FSFI) questionnaire was calculated for females. Data were analyzed via SPSS software. Two independent sample t-test with two-sided significance level of 5% was used for comparing the sexual dysfunction score between HD and PD patients.

Results: Out of 170 patients with mean age of 49.34 ± 11.7 years, 52.9% were female. Better sexual function scores were obtained in the HD group's females for desire, orgasm, and satisfaction domains, as well as the total score (P = 0.03, 0.016, 0.02, and 0.039, respectively). The erectile function was significantly better in the PD group's males (P).

Conclusion: We found better sexual life in the HD group's females and PD group's males. Considering dialysis as a life-long treatment of CKD patients, this part of a patient's life must be taken seriously by the healthcare providers to choose the most suitable method for patients based on their personalized conditions.