Whispering Tuberculosis

Ir Med J. 2021 Aug 19;114(7):418.

Abstract

Presentation We describe a case of reactivation of latent pulmonary tuberculosis (TB) invading the larynx and causing dysphonia. Diagnosis A previously healthy 30-year old woman was found to have bilateral pulmonary TB 5-months after being thoroughly investigated for hoarseness. Initial chest x-ray (CXR) and CT-neck were normal. Vocal cord biopsies were negative for granulomata. Treatment The patient was commenced on standard four drug Anti-TB treatment (ATT) and completed a one-year course. Unfortunately, the development of a laryngeal web caused persistent dysphonia. Discussion Patients with laryngeal TB are more likely to present to ENT surgeons, because of the initial symptom of hoarseness. Multiple tests must be completed before out-ruling TB. HRCT or sputum culture is recommended, as TB may not be evident on initial CXR. A collaborative approach between Respiratory and ENT teams is required. Prompt diagnosis is essential. Speech therapy input will be important in our patient's recovery.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dysphonia*
  • Female
  • Hoarseness / etiology
  • Humans
  • Sputum
  • Tuberculosis* / diagnosis
  • Tuberculosis, Pulmonary* / diagnosis
  • Tuberculosis, Pulmonary* / diagnostic imaging