The effect of plant-based diets on meta-inflammation and associated cardiometabolic disorders: a review

Nutr Rev. 2022 Aug 8;80(9):2017-2028. doi: 10.1093/nutrit/nuac020.

Abstract

Meta-inflammation is a chronic, low-grade state of inflammation secondary to cardiometabolic disorders related to overweight (OW), obesity (OB), consumption of poor nutritional and hypercaloric diets with excessive amounts of lipids and sugars. It can lead to severe metabolic and cardiovascular diseases. Several studies have reported that plant-based diets (PBDs) can be a useful non-pharmacological therapeutic tool for the prevention and treatment of meta-inflammation, since it has been reported that patients following PBDs have lower serum levels of proinflammatory markers, a reduction in weight, and an overall healthier lipid profile. In this review, we describe the pathophysiology of meta-inflammation, the growing worldwide trend toward adoption of PBDs, and how PBDs act to reduce meta-inflammation.

Keywords: cardiometabolics; diabetes; dyslipidemia; meta-inflammation; metaflammation; obesity; plant-based diet.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / prevention & control
  • Diet
  • Diet, Vegetarian
  • Humans
  • Inflammation
  • Overweight*