Case Report: successful use of phage therapy in refractory MRSA chronic rhinosinusitis

J Martin Rodriguez; Bradford A Woodworth; Bri'Anna Horne; Joseph Fackler; Michael J Brownstein

doi:10.1016/j.ijid.2022.04.049

Case Report: successful use of phage therapy in refractory MRSA chronic rhinosinusitis

Int J Infect Dis. 2022 Aug:121:14-16. doi: 10.1016/j.ijid.2022.04.049. Epub 2022 Apr 26.

Authors

J Martin Rodriguez¹, Bradford A Woodworth², Bri'Anna Horne³, Joseph Fackler³, Michael J Brownstein³

Affiliations

¹ University of Alabama at Birmingham, Birmingham, Alabama, USA. Electronic address: mrodriguez@uabmc.edu.
² University of Alabama at Birmingham, Birmingham, Alabama, USA.
³ Adaptive Phage Therapeutics, Gaithersburg, Maryland, USA.

PMID: 35472526
DOI: 10.1016/j.ijid.2022.04.049

Abstract

We present a case of refractory methicillin-resistant Staphylococcus aureus that was successfully treated with a combination of antibiotics, systemic phage and intranasal phage therapy.

Keywords: Bacteriophage; Chronic rhinosinusitis; Phage; Staphylococcus aureus.

Publication types

Case Reports

MeSH terms

Anti-Bacterial Agents / therapeutic use
Humans
Methicillin-Resistant Staphylococcus aureus*
Phage Therapy*
Sinusitis* / therapy
Staphylococcal Infections* / therapy

Substances

Anti-Bacterial Agents